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Saturday 30 November 2024
Salisbury Foundation Trust

FOI_7529

Internal Reference Number: FOI_7529

Date Request Received: 07/11/2023 00:00:00

Date Request Replied To: 16/11/2023 00:00:00

This response was sent via: By Email

Request Summary: acute myeloid leukaemia (AML) & chronic lymphocytic leukaemia (CLL)

Request Category: Companies

 
Question Number 1:
Patients with acute myeloid leukaemia (AML)
1. How many patients with AML, in total, have been treated with the following therapies during the last 6 months, irrespective of start date or line of therapy?
• Azacitidine monotherapy
• Low dose cytarabine (LoDAC) monotherapy
• Venetoclax + azacitidine
• Venetoclax + LoDAC
• Ivosidenib
• Intensive chemotherapy-based regimen
• Other
 
Answer To Question 1:
Q1
- Azacytidine monotherapy <5 patient (originally on venetoclax/azacytidine)
- Low dose cytarabine (LoDAC) monotherapy <5
- Venetoclax + Azacytidine 7
- Ivosidenib - <5
- Intensive chemotherapy based regimen <5
- Other <5
 
Question Number 2:
2. How many newly diagnosed patients with AML have started first-line treatment with the following therapies during the last 6 months?
• Azacitidine monotherapy
• Low dose cytarabine (LoDAC) monotherapy
• Venetoclax + azacitidine
• Venetoclax + LoDAC
• Ivosidenib
• Intensive chemotherapy-based regimen
• Other

Note: this should only include patients who have started first-line treatment during the 6-month window
 
Answer To Question 2:
Q2
Azacitidine monotherapy <5
Low dose Cytarabine <5
Venetoclax + Azacitidine <5
Venetoclax and LoDAC - <5
Ivosidenib - <5
Intensive chemotherapy based regimen <5
Other <5



 
Question Number 3:
3. Of the patients with AML treated with venetoclax (venetoclax + azacitidine or venetoclax + LoDAC) in the last 6 months, how many are approved for treatment via Blueteq?
 
Answer To Question 3:
8
 
Question Number 4:
Patients with chronic lymphocytic leukaemia (CLL)
4. How many patients with CLL have received treatment with venetoclax in the past 6 months (including venetoclax monotherapy, venetoclax + rituximab, venetoclax + obinutuzumab or venetoclax + ibrutinib)?

Note: this should include patients who started treatment prior to the 6-month window
 
Answer To Question 4:
14
 
Question Number 5:
5. How many patients with CLL who were new to all lines of treatment received venetoclax in the past 6 months (including venetoclax monotherapy, venetoclax + rituximab, venetoclax + obinutuzumab or venetoclax + ibrutinib)?

Note: this should include only patients who have started treatment during the 6-month window
 
Answer To Question 5:
6
 
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